Cardiac Stem Cell Therapy: A Brief Review of Clinical and Experimental Studies
نویسندگان
چکیده
Myocardial regeneration utilizing novel cell-based therapies, gene transfer, and growth factors may prove to play an important role in the management of heart disease. Clinical trials have been published for a variety of biologics methods: systemic infusion, intracoronary infusion, trans venous coronary sinus, and intramyocardial. This review aims to address the recent aspects of the relationships between cardiac stem cell therapy and cardiovascular disease.
منابع مشابه
Role of Stem Cells in Cardiac Cell Therapy and Tissue Engineering
Background: In spite of promising results of conventional treatments for myocardial infarction, including medications, stent implantation, and coronary artery bypass grafting, the disease and its complications, especially heart failure, are highly prevalent because these methods could not reverse the cell loss, which is the main problem. Currently, heart transplantation, as the last option f...
متن کاملImmunomodulatory Effect of Mesenchymal Stem Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: A Review Study
Multiple Sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system that may lead to disability of the patient. Current MS treatment regimens are still insufficient and research is conducted for developing more effective therapies capable of targeting neurodegeneration, inflammation, and demyelination. Recent results of experimental and clinical studies in ...
متن کاملCell Therapy for Traumatic Brain Injury: Opportunities and Pitfalls
Today, stem cell transplantation is a hot topic in scientific circles as a novel therapeutic approach to repair the structure and function of central nervous system. The safe and neuroprotective effects of cell therapy in models and traumatic brain injury patients were evaluated in many experimental and clinical studies in recent decade and somewhat promising results were provided to the scient...
متن کاملO 9: Immunomodulatory Effects of Neural Stem Cell on Multiple Sclerosis: A Systematic Review
Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are chronic inflammatory demyelinating disorders of central nervous system (CNS). While the cause is unclear, the fundamental mechanism is thought to be destruction of myelin sheaths of neurons through immune system. One of the approaches being proposed in EAE therapy is neural stem cells (NSCs) trans...
متن کاملA Brief Review of New Advances in the Treatment of Spinal Cord Injuries
Introduction: Spinal Cord Injuries (SCIs) are the main factor in the sensory disorders, which are caused by spinal cord strikes such as car accidents. Previously it was thought that SCIs could not be treated. However, new advances in neurology showed possible treatment to relieve pain in these patients. This article presents a brief review about physiology of spinal cord, kinds of injuries and ...
متن کاملAN OVERVIEW OF STEM CELL AND REGENERATIVE MEDICINE RESEARCHES IN IRAN
Background: In many years, finding modern and appropriate treatments for diseases, especially chronic diseases (such as chronic metabolic diseases) have been one of the most important issues. On the other hand, limitations related to organ transplantation have made a serious need for advanced therapeutic strategies. In this respect, researchers have recognized the benefits of stem cells as a su...
متن کامل